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Index > Protein center > HTR2A(Gene name) > Dog
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  • HTR2A (Gene name),
  • 5-hydroxytryptamine receptor 2A (Protein name ),  5HT2A_CANFA from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    HTR2A(5-HTR2A);
    Protein name:
    5-hydroxytryptamine receptor 2A(5-HT-2;5-HT-2A;5-hydroxytryptamine receptor);
    Alternative:
    Serotonin receptor 2A;
    Organism:
    Dog (Canis familiarisCanis lupus familiaris). 
    General Annotation
    Sub Unit:
    Interacts with MPDZ and INADL. May interact with MPP3, PRDX6, DLG4, DLG1, CASK, APBA1 and MAGI2.
    Function:
    This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. This receptor is involved in tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production.
    Subcellular Location:
    Cell membrane Multi-pass membrane protein Localizes to the post-synaptic thickening of axo-dendritic synapses.
    Protein Attributes:
    Sequence length:
    470
    Sequence:
    50:
    MDVLFEDNAP | LSPTTSSLMP | SNGDPRLYGN | DLNAGDANTS | DAFNWTVDAE | 
    100:
    NRTNLSCEGC | LSPPCFSLLH | LQEKNWSALL | TAVVIILTIA | GNILVIMAVS | 
    150:
    LEKKLQNATN | YFLMSLAIAD | MLLGFLVMPV | SMLTILYGYR | WPLPSKLCAV | 
    200:
    WIYLDVLFST | ASIMHLCAIS | LDRYVAIQNP | IHHSRFNSRT | KAFLKIIAVW | 
    250:
    TISVGISMPI | PVFGLQDDSK | VFKEGSCLLA | DDNFVLIGSF | VSFFIPLTIM | 
    300:
    VITYFLTIKS | LQKEATLCVS | DPGTRAKLAS | FSFLPQSSLS | SEKLFQRSIH | 
    350:
    REPGSYGRRT | MQSISNEQKA | CKVLGIVFFL | FVVMWCPFFI | TNIMAVICKE | 
    400:
    SCNEDIIGAL | LNVFVWIGYL | SSAVNPLVYT | LFNKTYRSAF | SRYIQCQYKE | 
    450:
    NKKPLQLILV | NTIPALAYKS | SQLQMGQKKN | SKKDAKSTDN | DYSMVALGKQ | 
    470:
    HSEDAPTDNI | NTVNEKVSCV | 
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Dog 5-HT-2
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    E10283h
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    ELISA Kit for Dog 5-HT-2
    Cat.:
    E10283r
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    96T
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    ELISA Kit for Dog 5-HT-2
    Cat.:
    E10283d
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    96T
    ELISA Kit for Dog 5-HT-2
    Cat.:
    E10283m
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    96T
    ELISA Kit for Dog 5-HT-2
    Cat.:
    E10283p
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    96T
    ELISA Kit for Dog 5-HT-2
    Cat.:
    E10283b
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    Packing:
    96T
    CLIA Kit for Dog 5-HT-2
    Cat.:
    U10283p
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Dog 5-HT-2
    Cat.:
    U10283r
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    Packing:
    96T
    CLIA Kit for Dog 5-HT-2
    Cat.:
    U10283h
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Dog 5-HT-2
    Cat.:
    U10283b
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Dog 5-HT-2
    Cat.:
    U10283d
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Dog 5-HT-2
    Cat.:
    U10283m
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Dog 5-HT-2
    Polyclonal Antibody for Dog 5-HT-2
    Cat.:
    P10283Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Dog 5-HT-2
    Polyclonal Antibody for Dog 5-HT-2
    Cat.:
    P10283Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Dog 5-HT-2
    Polyclonal Antibody for Dog 5-HT-2
    Cat.:
    P10283Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Dog 5-HT-2
    Monoclonal Antibody for Dog 5-HT-2
    Monoclonal Antibody for Dog 5-HT-2
    Monoclonal Antibody for Dog 5-HT-2
    Monoclonal Antibody for Dog 5-HT-2
    Monoclonal Antibody for Dog 5-HT-2
    Protein for Dog 5-HT-2
    Protein for Dog 5-HT-2
    Protein for Dog 5-HT-2
    Protein for Dog 5-HT-2
    Protein for Dog 5-HT-2
    Protein for Dog 5-HT-2

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    References
    1. 1.
      "Sequencing of canine 5-hydroxytriptamine receptor (5-HTR) 1B, 2A, 2C genes and identification of polymorphisms in the 5-HTR1B gene."
      Masuda K. , Hashizume C. , Ogata N. , Kikusui T. , Takeuchi Y. , Mori Y.
      J. Vet. Med. Sci.66:965-972(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Beagle.
    2. 2.
      "Molecular and pharmacological characterization of serotonin 5-HT(2A) and 5-HT(2B) receptor subtypes in dog."
      Bonaventure P. , Nepomuceno D. , Miller K. , Chen J. , Kuei C. , Kamme F. , Tran D.T. , Lovenberg T.W. , Liu C.
      Eur. J. Pharmacol.513:181-192(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
    3. 3.
      Sgard F.
      Submitted (1998-01) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 120-307
      tissue: Femoral artery.
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